Enabling increased throughput and online quality control
One of our current projects is to implement microfluidic principles to our BioRam® system, allowing for the development of tailored chips and filter systems to be used in combination with its analytical platforms.
Dedicated fluid-filled slides with microchannels allow living cells to be analyzed repetitively to monitor cellular response to drug application or to study stem cell differentiation. In further applications, cells can be transported gently and analyzed one-by-one in a continuous flow approach, and can be sorted contact-free, according to the analytical results.
We also work on developing specific microfluidic filters that help separate biological contaminants – bacteria, fungi and spores– from in-vitro grown tissues and aggregate them in one layer so that they can be detected reliably by Raman spectroscopy.