Quality control: Cell and tissue cultures
In contrast to common histological, immunohistochemical and biochemical methods, CellTool’s systems allow cultured tissues to be analysed non-invasively, without any loss of cultured cells. The time- and cost-intensive practice of creating a second tissue culture for destructive quality control becomes obsolete. Moreover, Raman spectroscopy was shown to deliver superior analytical outcomes in various applications.
Among others, it was successfully applied to…
evaluate the purity and viability of chondrocytes and their differentiation state in autologous cartilage transplants.
identify living primary human skin fibroblasts, keratinocytes, and melanocytes, as well as immortalized keratinocytes, which is highly relevant for engineering in vitro skin models or producing artificial skin.
detect a contamination of stromal fibroblasts in a culture of mesenchymal stem cells.