Technology

LEARN ABOUT OUR TECHNOLOGY

BioRam® TECHNOLOGY

Get a unique ‘metabolomic fingerprint’ from your cells

BioRam® makes Raman spectroscopy as simple as light microscopy. This unique Raman-Trapping microscope provides biologists and physicians with fast and easy information about cell kind, cell state, cell behavior and cell reaction upon drugs or toxins.

 
BIORAM® IST DESIGNED BY BIOLOGISTS ESPECIALLY FOR BIOMEDICAL APPLICATIONS.
  • intuitive user interface 

  • integrated Optical Trap allows Raman spectra acquisition of samples in solution – even of motile bacteria 

  • cells of interest can be positioned and isolated alive and undamaged for further use

GET COMPLETE INSIGHT INTO YOUR SAMPLE: 
  • specific information about the overall chemical composition of cells, solids and fluidics

  • precise results – in 2D and 3D cell culture, and tissues

  • work with small amounts of sample (100 cells)

  • analyze eukaryotic, prokaryotic as well as plant cells

without:

  • modification of cell surfaces or activity states

  • destruction of the sample

  • time- and cost intense sample staining or antibody based labeling

BIORAM® WILL CHANGE THE WAY OF SAMPLES ANALYSIS.

​In close cooperation with our customers hardware and software features are continuously adapted to meet specific requirements: 

Get the BioRam® YOU need:

  • tailored platforms for various applications

  • modular system dedicated to your requirements.

Modules are:

  • environmental control (temperature, CO/O2)

  • fluorescence unit (switch between 4 available fluorescence channels)

  • microfluidic​

Service:

  • first-class customer support

  • customer workshops and application laboratory

BIO RAM TECHNOLOGY

Get a unique ‘metabolomic fingerprint’ from your cells

BioRam® makes Raman spectroscopy as simple as light microscopy. This unique Raman-Trapping microscope provides biologists and physicians fast and easy information about cell kind, cell state, cell behaviour and cell reaction upon drugs or toxins.

RAMAN TECHNOLOGY

How it works.

Perfect blend of complementary technologies – Raman Spectroscopy

and Optical Tweezers

  • STEP 1

    A cell is exposed to laser light.

  • STEP 2

    The photons interact with the biomolecules in the cell.

     

  • STEP 3

    In this process some of the photons loose energy. 

    This decrease in energy can be measured as an increase in wavelength.

  • STEP 4

    In Raman spectroscopy, these shifts are recorded as wavelength spectra (Raman spectra).

  • STEP 5

    Biomolecules exhibit characteristic Raman spectra. Consequently, Raman spectra can be used to distinguish between for examples different cell types or cell states.

 
Contact us
Location
Contact us

CellTool GmbH

Lindemannstraße 13

82327 Tutzing

Germany

info@celltool.de
 +49 (0) 8158 906400